Space-Time Cluster Analysis of Invasive Meningococcal Disease

نویسندگان

  • Christian J.P.A. Hoebe
  • Hester de Melker
  • Lodewijk Spanjaard
  • Jacob Dankert
  • Nico Nagelkerke
چکیده

Clusters are recognized when meningococcal cases of the same phenotypic strain (markers: serogroup, serotype, and subtype) occur in spatial and temporal proximity. The incidence of such clusters was compared to the incidence that would be expected by chance by using space-time nearest-neighbor analysis of 4,887 confirmed invasive meningococcal cases identified in the 9-year surveillance period 1993-2001 in the Netherlands. Clustering beyond chance only occurred among the closest neighboring cases (comparable to secondary cases) and was small (3.1%, 95% confidence interval 2.1%-4.1%).

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عنوان ژورنال:

دوره 10  شماره 

صفحات  -

تاریخ انتشار 2004